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KMID : 0614620110570030166
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Korean Journal of Gastroenterology
2011 Volume.57 No. 3 p.166 ~ p.172
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The Seroprevalence Rate, Vaccination Rate and Seroconversion Rate of Hepatitis A in Central Region of Korea
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Yun Seung-Wook
Lee Won-Kyung
Cho Sun-Young
Moon Sung-Hoon
Shin Hyun-Deok
Yun Se-Young
Kim Suk-Bae
Shin Jeong-Eun
Kim Hong-Ja
Song Il-Han
Lee Kun-Song
Lee Jae-Hyun
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Abstract
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Background/Aims: Acute hepatitis A (HAV) is markedly increasing recently on. Some patients with acute hepatitis A show severe clinical course. The seroprevalence rate of IgG anti-HAV has been changing with the regions and the times. Vaccination and seroconversion rate of HAV are not well known. In this study, we aimed to study the difference of seroprevalence rate of IgG anti-HAV according to various clinical factors and to know the vaccination rate and seroconversion rate below 10 years old in the central region of South Korea including Cheonan city.
Methods: Seven hundred seventy two subjects were included in the study from January to September 2009. We analyzed seroprevalence rate of IgG anti-HAV according to sex, age, region, and other viral markers. We interviewed the history of vaccination(1st, 2nd) and analyzed seroconversion rate according to vaccination time below 10 years old.
Results: The total seroprevalence rate of IgG anti-HAV was 65.3%. The seroprevalence rate of IgG anti-HAV rate in 2nd, 3rd, and 4th decade was very low (1.9%, 18.8%, 44.8%). The vaccination rate of children was about 50%. The seroconversion rate after 1st, and 2nd vaccination were 85%, 96%.
Conclusions: Catch-up vaccination for teenagers and young adults is needed. Immunizing children with HAV vaccine as a routine schedule should be considered.
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KEYWORD
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Seroprevalence rate, Vaccination rate, Seroconversion rate, Hepatitis A
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